The human gut microbiome significantly affects our health. Fiber intake plays an important role here, yet identifying the optimal fiber mix for gut health is challenging. Here we aim to conduct in vivo, ex vivo and in vitro studies on various fibers to study how specific cazymes present in the gut microbes break down fibers and modulate the gut microbiome. This information will be used to develop an AI model to predict fiber combinations that will modulate the gut microbiome towards health.